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Selenium Test

Selenium Test

February 2, 2026
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Do I need a Selenium test?

Feeling fatigued, struggling with brain fog, or noticing your immune system isn't what it used to be? Could low selenium be affecting your thyroid, immunity, and overall vitality?

Selenium is a powerful antioxidant that supports your thyroid function, immune defense, and protects your cells from damage. When levels are off, you may experience fatigue, weakened immunity, or cognitive issues.

Testing your selenium gives you a quick snapshot of whether deficiency is contributing to your symptoms. It's the essential first step to personalizing your nutrition and lifestyle choices, so you can restore your energy and resilience.

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Get tested with Superpower

If you’ve been postponing blood testing for years or feel frustrated by doctor appointments and limited lab panels, you are not alone. Standard healthcare is often reactive, focusing on testing only after symptoms appear or leaving patients in the dark.

Superpower flips that approach. We give you full insight into your body with over 100 biomarkers, personalized action plans, long-term tracking, and answers to your questions, so you can stay ahead of any health issues.

With physician-reviewed results, CLIA-certified labs, and the option for at-home blood draws, Superpower is designed for people who want clarity, convenience, and real accountability - all in one place.

Key benefits of Selenium testing

  • Reveals whether your selenium level supports immune defense and thyroid function.
  • Spots deficiency that may explain fatigue, brain fog, or weakened immunity.
  • Flags excess selenium, which can cause hair loss, nausea, or nerve symptoms.
  • Guides supplementation decisions to avoid both deficiency and toxicity risks.
  • Protects fertility by ensuring adequate selenium for sperm quality and egg health.
  • Tracks selenium status if you have thyroid disease or autoimmune conditions.
  • Clarifies whether low selenium contributes to muscle weakness or mood changes.
  • Best interpreted with thyroid panel and your symptoms for full clinical context.

What is Selenium?

Selenium is an essential trace mineral that your body cannot make on its own. You obtain it through food, primarily from Brazil nuts, seafood, meat, and grains grown in selenium-rich soil. Once absorbed, selenium is incorporated into specialized proteins called selenoproteins that are distributed throughout your tissues.

Your body's built-in antioxidant defense

Selenium is a key component of glutathione peroxidase and other antioxidant enzymes that protect your cells from oxidative damage. It also supports thyroid hormone production, immune function, and DNA synthesis.

A mineral that works through proteins

Unlike vitamins that act directly, selenium functions by becoming part of at least 25 different selenoproteins. These proteins act as molecular tools that regulate metabolism, neutralize harmful free radicals, and help maintain healthy inflammation responses.

Blood selenium levels reflect your recent dietary intake and your body's selenium stores. Because selenium is critical for so many protective systems, measuring it helps assess whether you're getting enough of this vital nutrient to support optimal cellular function.

Why is Selenium important?

Selenium is a trace mineral that functions as a cofactor for antioxidant enzymes, particularly glutathione peroxidases, which protect cells from oxidative damage throughout the body. It plays essential roles in thyroid hormone metabolism, immune function, DNA synthesis, and reproductive health. Without adequate selenium, your cells become vulnerable to inflammation and metabolic dysfunction.

Your thyroid can't work without it

Normal selenium levels typically range from 70 to 150 micrograms per liter, with optimal function often seen in the middle to upper portion of this range. When selenium is low, thyroid hormone conversion slows, leading to fatigue, weight gain, cold intolerance, and brain fog. Low levels also weaken immune defenses, increase infection risk, and may impair fertility in both men and women. Pregnant women with insufficient selenium face higher risks of miscarriage and developmental issues in the baby.

Too much selenium is toxic

Elevated selenium, usually from oversupplementation, causes selenosis - a toxic state marked by hair loss, brittle nails, garlic breath, nausea, and neurological symptoms. Chronic excess can damage the liver and nervous system.

A small nutrient with whole-body reach

Selenium status reflects the balance between dietary intake and metabolic demand. It intersects with iodine for thyroid health, with vitamin E for antioxidant defense, and with immune surveillance against infections and cancer. Long-term deficiency accelerates aging, cardiovascular disease, and autoimmune thyroid conditions.

What do my Selenium results mean?

Low selenium usually reflects inadequate intake or absorption

Low values usually reflect insufficient dietary intake, poor absorption from the gut, or increased losses through chronic illness or kidney dialysis. Selenium is essential for making selenoproteins, which protect cells from oxidative damage and support thyroid hormone activation. When levels drop, the thyroid may struggle to convert inactive T4 into active T3, leading to sluggish metabolism even when TSH appears normal. Low selenium also weakens immune defenses and may contribute to muscle weakness, fatigue, and increased vulnerability to infections. Deficiency is more common in regions with selenium-poor soil and in people with digestive disorders that impair mineral absorption.

Optimal selenium supports antioxidant defense and thyroid function

Being in range suggests adequate intake and efficient incorporation into selenoproteins like glutathione peroxidase and thioredoxin reductase. These enzymes protect tissues from oxidative stress and support healthy thyroid hormone metabolism, immune surveillance, and reproductive function. Optimal levels tend to sit in the mid to upper portion of the reference range for most populations.

High selenium usually reflects excessive supplementation

High values usually reflect overzealous supplementation or, rarely, environmental overexposure. Excess selenium can cause nausea, brittle nails, hair loss, fatigue, and a garlic-like breath odor. Chronic toxicity may impair glucose metabolism and increase cardiovascular risk.

Interpretation depends on assay type and clinical context

Whole blood selenium reflects recent intake, while plasma or serum levels respond more quickly to changes. Results may be lower during acute illness or pregnancy.

Method: Laboratory-developed test (LDT) validated under CLIA; not cleared or approved by the FDA. Results are interpreted by clinicians in context and are not a stand-alone diagnosis.

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Similar biomarker tests from Superpower

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Frequently Asked Questions

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How it works
What should I expect during a blood draw?
  • A trained phlebotomist will guide you through the process.
  • A tourniquet is placed on your arm, the site is cleaned, and a small needle is used to collect blood into one or more tubes.
  • Results are usually ready in about a week.
  • Most people feel only a quick pinch.
  • The needle is removed, gentle pressure is applied, and a bandage is placed.
How do I prepare for a blood draw?
  • Drink plenty of water beforehand — hydration makes veins easier to find.
  • Wear loose sleeves so your arm is easy to access.
  • Follow any fasting instructions you’ve been given.
  • Let us know if you’re on medications, have fainted before, or have needle anxiety.
What should I do after my blood draw?
  • Press gently on the site for a few minutes.
  • Keep the bandage on for 4-6 hours.
  • Skip heavy lifting or strenuous exercise for the rest of the day.
  • Drink extra water to rehydrate.
  • Monitor the site for redness, swelling, or pain.
How do I book a blood draw with Superpower?

Your membership includes:

  • An annual full body test and report across 100+ biomarkers
  • A personalized action plan to optimize your biomarkers and reach your health goals
  • A dashboard to centralize your health data and track changes across a lifetime
  • Access to a health concierge for questions on your plan and help scheduling
  • Plus a marketplace of curated health products and services cheaper than amazon

Many concierge clinics charge $10k – $100k for their services, we’ve built technology to make the world’s best healthcare as accessible as possible via an all-in-one membership.

Where can I take my blood test?

Superpower is currently available in the following US states:

  • Alabama
  • Arizona
  • California
  • Colorado
  • Connecticut
  • Delaware
  • District of Columbia
  • Florida
  • Georgia
  • Idaho
  • Illinois
  • Indiana
  • Kansas
  • Maine
  • Maryland
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  • Michigan
  • Minnesota
  • Missouri
  • Montana
  • Nebraska
  • Nevada
  • New Hampshire
  • New Jersey
  • New Mexico
  • New York
  • North Carolina
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • South Carolina
  • Tennessee
  • Texas
  • Utah
  • Vermont
  • Virginia
  • Washington
  • West Virginia
  • Wisconsin
Our testing
Does Superpower replace my primary care provider?

Superpower specializes in prevention-based testing and treatments and is not intended for emergency or immediate health issues.

While you will have a Superpower care team, your annual membership is designed to complement a primary care doctor if you have one, not replace them.

We are happy to help you share any test results with an outside provider to ensure you receive well-rounded medical care.

How fast are blood test results and how do I read them?

Your annual lab test panel takes about a week to process. We will text you as soon as they become available in your dashboard. Other types of tests may have different testing windows. The Superpower concierge is your own health assistant who helps answer your questions on your results, ensure smooth scheduling, coordination of any office-based tests, specialist referrals as needed, and navigating you to interface with your care team.

Does Superpower accept health insurance?

Superpower membership and products are all eligible for HSA/FSA funding.

We see Superpower like a gym membership for those committed to prevention and performance. Superpower is a bridge between wellness and healthcare. Health insurance traditionally focuses on reactive care whereas, at Superpower, we believe it’s never too early to start looking out for your long-term health.

What if I want more than 1 blood test per year?

Absolutely — you're not limited to just one. Your membership includes one comprehensive 100+ biomarker blood test each year, but if you'd like to track your progress more closely, you can add extra tests at any time. Each additional full-panel test costs $179. You can order as many as you'd like throughout the year.

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Frequently Asked Questions about Selenium Test

What is selenium and what does selenium do in the body?

Selenium is an essential trace mineral your body can’t make, so you must get it from food. After absorption, it’s built into at least 25 selenoproteins that act as “molecular tools” in your tissues. Selenium supports antioxidant defenses (including glutathione peroxidase), thyroid hormone production and conversion, immune function, DNA synthesis, and reproductive health. Because it works through selenoproteins, both low and high selenium can disrupt multiple systems.

What are the key benefits of getting a blood selenium test?

A blood selenium test helps reveal whether your selenium status supports immune defense and thyroid function, and it can identify deficiency that may contribute to fatigue, brain fog, muscle weakness, mood changes, or frequent infections. Testing can also flag excess selenium (selenosis risk), which may cause hair loss, nausea, and nerve symptoms. Results can guide supplementation decisions and help track selenium status in thyroid disease or autoimmune conditions.

What are normal blood selenium levels, and what range is considered optimal?

Typical blood selenium levels are often about 70 to 150 micrograms per liter, though lab ranges can vary. The context notes that optimal function is commonly seen in the middle to upper portion of the reference range. Being in range generally supports antioxidant capacity, thyroid hormone metabolism, and immune resilience. Interpretation should be combined with your symptoms and, when relevant, a thyroid panel for fuller clinical context.

What symptoms can low selenium cause, and how can deficiency affect thyroid health?

Low selenium can reduce selenoprotein activity, increasing oxidative stress and weakening immune surveillance. Symptoms may include fatigue, brain fog, muscle weakness, hair loss, frequent infections, and mood changes. Selenium is important for thyroid hormone conversion (T4 to active T3), so low levels may contribute to sluggish metabolism, cold intolerance, and low energy - even when standard thyroid tests look “normal.” Deficiency can also affect fertility in men and women.

How do I know if I have too much selenium, and what is selenosis?

High selenium is most often due to oversupplementation and, more rarely, environmental or occupational exposure. Selenium toxicity is called selenosis and can cause brittle nails, hair loss, garlic breath odor, nausea or digestive upset, fatigue, and neurological symptoms like numbness or irritability. Chronic excess may disrupt antioxidant balance and may impair glucose metabolism, potentially increasing diabetes risk, and may raise cardiovascular risk.

Which foods are high in selenium, and why does geography affect selenium intake?

Selenium comes primarily from foods like Brazil nuts, seafood, meat, and grains - especially when grown in selenium-rich soil. Geography matters because soil selenium content differs by region, changing how much selenium ends up in crops and animal feed. This means two people eating similar diets in different locations can have different baseline selenium intake. Because of this variability, blood selenium testing can help clarify whether intake is adequate.

How should I interpret selenium test results alongside a thyroid panel and symptoms?

Selenium results are best interpreted with your symptoms and thyroid testing because selenium directly supports thyroid hormone metabolism and antioxidant protection in thyroid tissue. Low selenium may contribute to poor T4-to-T3 conversion, fatigue, and immune changes. Normal selenium suggests adequate antioxidant and thyroid support. High selenium raises concern for selenosis, especially if symptoms like hair loss or garlic breath are present. Context emphasizes combining selenium results with a thyroid panel for clinical context.

What can cause low selenium levels besides not eating enough selenium-rich foods?

Low selenium can reflect inadequate intake, poor absorption, or increased losses. The context specifically notes chronic illness and dialysis as potential contributors. Certain conditions like inflammatory bowel disease and critical illness can lower measured selenium levels without true deficiency, and some medications may also affect levels. Because multiple factors can influence results, selenium status should be interpreted in context rather than relying on a single number alone.

How does selenium support fertility and reproductive health in men and women?

Selenium helps protect reproductive tissues from oxidative damage through antioxidant enzymes and supports overall cellular function. Low selenium can impair sperm quality in men and may disrupt ovarian function in women, affecting fertility. The context also notes that low selenium may increase miscarriage risk during pregnancy. Maintaining adequate (but not excessive) selenium helps support sperm quality, egg health, and healthy inflammatory balance important for reproductive outcomes.

Is it safe to take selenium supplements, and how can I avoid deficiency and toxicity?

Supplementation can be helpful when a test shows low selenium or when intake is insufficient, but too much selenium can cause toxicity. The context highlights that high selenium is commonly due to oversupplementation and can lead to selenosis (hair loss, brittle nails, garlic breath, nausea, neurological symptoms). Using blood selenium testing to guide decisions helps avoid both deficiency and excess, especially if you have thyroid disease or autoimmune conditions.

Finally, healthcare that looks at the whole you