Get tested with Superpower

**If you’ve been postponing blood testing for years or feel frustrated by doctor appointments and limited lab panels, you are not alone.** Standard healthcare is often reactive, focusing on testing only after symptoms appear or leaving patients in the dark.

Superpower flips that approach. We give you full insight into your body with over **100 biomarkers**, personalized action plans, long-term tracking, and answers to your questions, so you can stay ahead of any health issues.

With physician-reviewed results, CLIA-certified labs, and the option for at-home blood draws, Superpower is designed for people who want clarity, convenience, and real accountability - all in one place.

Key benefits of Progesterone testing

• Confirms whether ovulation occurred during your menstrual cycle.
• Spots hormonal imbalances that may explain irregular periods or missed cycles.
• Clarifies causes of unexplained infertility or difficulty conceiving.
• Guides treatment decisions for luteal phase defects affecting early pregnancy support.
• Tracks early pregnancy health and flags risk of miscarriage or ectopic pregnancy.
• Explains symptoms like abnormal bleeding, mood changes, or premenstrual issues.
• Best interpreted with cycle timing, symptoms, and tests like LH or estradiol.

What is Progesterone?

Progesterone is a steroid hormone produced primarily by the ovaries after ovulation, with smaller amounts made by the adrenal glands. In pregnancy, the placenta becomes the major source. It belongs to a class of hormones called progestogens, which prepare the body for conception and sustain early pregnancy.

The hormone that prepares for pregnancy

Progesterone transforms the uterine lining (endometrium) into a nutrient-rich environment where a fertilized egg can implant and grow. It also stabilizes the uterus by reducing contractions that might expel an embryo.

A key player in the menstrual cycle

After ovulation, progesterone levels rise sharply during the second half of the menstrual cycle (luteal phase). If pregnancy doesn't occur, progesterone drops, triggering menstruation. If pregnancy begins, progesterone stays elevated to support the developing embryo.

Beyond reproduction

Progesterone also influences mood, sleep, and bone health. It interacts with receptors in the brain and other tissues, contributing to overall hormonal balance in both women and men, though at much lower levels in males.

Why is Progesterone important?

Progesterone is a steroid hormone that prepares the body for pregnancy and regulates the menstrual cycle, but it also influences mood, sleep, bone health, and metabolic balance in both women and men. In women, levels fluctuate dramatically across the cycle - rising after ovulation to support the uterine lining - while in men and children, progesterone remains consistently low. Optimal values depend entirely on timing: mid-luteal phase levels in cycling women typically range from 5 to 20 ng/mL, while follicular phase, postmenopausal, and male values stay below 1 ng/mL.

When progesterone runs low

Insufficient progesterone in the luteal phase signals weak or absent ovulation, leading to irregular periods, heavy bleeding, and difficulty conceiving or maintaining early pregnancy. Women may experience premenstrual mood swings, anxiety, insomnia, and breast tenderness as estrogen goes unopposed. Over time, low progesterone contributes to endometrial hyperplasia and increased miscarriage risk.

When progesterone climbs high

Elevated progesterone outside of pregnancy or the luteal phase may indicate ovarian cysts, adrenal tumors, or congenital adrenal hyperplasia. During pregnancy, progesterone rises steadily to sustain the placenta, but abnormally high levels can cause fatigue, bloating, and constipation.

The bigger hormonal picture

Progesterone works in concert with estrogen, thyroid hormones, and cortisol to regulate reproductive health, bone density, and metabolic function. Chronic imbalances increase long-term risks for osteoporosis, cardiovascular disease, and hormone-sensitive cancers, making progesterone a key marker of endocrine and reproductive vitality.

What do my Progesterone results mean?

Low progesterone levels

Low values usually reflect reduced ovarian production after ovulation or inadequate corpus luteum function. In menstruating women, this often signals anovulation (cycles without ovulation) or a weak luteal phase, which can affect menstrual regularity and fertility. During pregnancy, low progesterone may indicate risk of miscarriage or placental insufficiency. In men and postmenopausal women, progesterone is naturally very low and has limited clinical significance.

Optimal progesterone levels

Being in range suggests healthy ovulation and adequate corpus luteum function in the second half of the menstrual cycle. Optimal values vary dramatically by cycle phase: progesterone should be low in the follicular phase and rise significantly after ovulation during the luteal phase. In pregnancy, sustained elevation supports uterine lining stability and fetal development. Timing of the test relative to ovulation or pregnancy stage is essential for meaningful interpretation.

High progesterone levels

High values usually reflect normal luteal phase physiology, early pregnancy, or ovarian cysts that produce excess hormone. Rarely, adrenal tumors or certain medications can elevate progesterone. Persistently high levels outside of pregnancy may indicate luteal cysts or hormonal imbalances affecting cycle regularity.

Factors that influence progesterone results

Progesterone fluctuates widely across the menstrual cycle, so timing is critical. Pregnancy, hormone therapy, and certain medications alter levels significantly. Lab methods vary, and single measurements provide limited information without clinical context or serial testing.