Vitamin B12

Boost your energy and support your nervous system with Vitamin B12, an essential nutrient that helps your body convert food into fuel and keeps you feeling your best.

December 5, 2025
Author
Superpower Science Team
Reviewed by
Julija Rabcuka
PhD Candidate at Oxford University
Creative
Jarvis Wang

Key Facts

  • Vitamin B12 is an essential nutrient that supports nerve function, blood cell formation, and cardiovascular health
  • This formulation uses methylcobalamin, the active form your body can use immediately, rather than cyanocobalamin which requires liver conversion
  • Methylcobalamin supports healthy sleep cycles and helps regulate homocysteine, a marker linked to heart health
  • Your body retains methylcobalamin more efficiently, with about one-third the urinary loss compared to other B12 forms

Ingredients

Vitamin B12 (as methylcobalamin) 1 mg per capsule.

Why We Chose This

Most B12 supplements rely on cyanocobalamin, which your liver must first detoxify and convert before your cells can actually use it. This formulation skips that step by providing methylcobalamin, the form your body recognizes and absorbs directly. Research shows that while both forms deliver similar amounts of B12 initially, methylcobalamin accumulates significantly more in your tissues and is excreted at roughly one-third the rate, meaning your body holds onto it longer. For anyone concerned with energy, sleep quality, or cardiovascular markers like homocysteine, this bioavailable approach offers a more efficient pathway to supporting these systems.

Frequently Asked Questions About Vitamin B12

What is the supporting research for the benefits of vitamin B12?
How do I take vitamin B12?

Take 1 capsule one to three times daily, or follow your health professional's recommendation for your specific needs.

Methylcobalamin in this form bypasses liver conversion, allowing your body to use it more efficiently than standard cyanocobalamin supplements.

Can I take vitamin B12 with other supplements or medications?

B12 generally pairs well with most supplements and medications, though certain drugs like acid reducers and metformin may interfere with absorption. Always discuss your full supplement regimen with your healthcare provider.

Who might benefit from taking vitamin B12?

Older adults, vegetarians and vegans, and people with absorption issues like celiac or Crohn's disease benefit most from B12 supplementation. Those with deficiency-related fatigue or nerve concerns also see meaningful support from adequate B12 levels.

How long does it typically take to notice effects of vitamin B12?

Oral B12 supplements typically show noticeable effects within 2 to 4 weeks, though some people report initial energy shifts within days. Full tissue saturation and symptom resolution can take several weeks to months depending on deficiency severity and individual absorption.

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