Method: ICP-MS (Inductively Coupled Plasma Mass Spectrometry) with creatinine normalization by Jaffe Reaction (CLIA 14D0646470); not cleared or approved by the FDA. Results in µg/g creatinine; reference intervals based on NHANES population data under non-provoked conditions. Not a stand-alone diagnosis; should be interpreted in clinical context.
A derived biomarker is a value that is calculated from other directly measured biomarkers rather than being measured directly in the lab.
Key benefits of Thallium (Tl) testing
- Thallium exposure tracking
- soil-contaminated food and industrial exposure assessment
- highly toxic metal monitoring
What is Thallium (Tl)?
Thallium is a highly toxic heavy metal with no safe biological role. Dietary exposure can occur through food grown in thallium-contaminated soil - particularly certain vegetables like green leafy vegetables, cabbage, and root vegetables. Industrial and occupational sources also exist. Measured via ICP-MS.
Why is Thallium (Tl) important?
Thallium is acutely and chronically toxic and has been used historically as a rodenticide (now banned in many countries). Even low chronic dietary exposure from contaminated soil may be relevant to health. Monitoring thallium provides important information given its high toxicity relative to other metals.
What insights will I get?
Your urinary thallium level may reflect dietary intake from produce grown in thallium-containing soils or industrial exposure. Discuss any elevated thallium finding with your care team - this metal has high toxicity relative to others in this panel.
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