Superpower vs Hone Health

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Superpower Logo
Hone Health
Annual baseline test
150+ biomarkers*
50+ biomarkers, hormone-weighted
Testing location
2,000+ partner labs (or at-home draw, paid add-on)
2,000+ national lab locations (or an in-home GetLabs draw, free for initial labs only, where available)
Action plan
Superpower's proprietary action plan
Provider-guided treatment plan
On-demand access to care team
Unlimited messaging on Premium
Follow-up test
Built-in follow-up draw retesting ~60 biomarkers, included in the membership
50+ biomarker retest, cadence varies by tier (Premium vs. Basic)
Curated supplement marketplace with member-exclusive pricing
Premium supplements via membership
Access to personalized prescription Rx medications
Medications priced separately
TRT, HRT, GLP-1
Data visualization
Access to gut microbiome testing
Add-on
Not included
Cost
$349
$65 assessment + $25-$155/mo membership
Start testing

*Includes direct laboratory measurements and calculated health metrics. Superpower's 150+ reflects combined tests across an initial draw and a built-in retest of the same markers. Comparison based on publicly available information as of 9/1/2026.

Key takeaway:

Hone Health centers on hormones: a $65 assessment of 50+ markers across several body systems, with a hormone-led care model and telehealth physicians for TRT, HRT, and related care, with medication billed separately. However, if you're looking for more post-testing actionable support at a lower price, Superpower is $349/year and tests 150+ whole-body health metrics across an initial complete draw plus a built-in follow-up draw, pairing a personalized action plan with on-demand care-team messaging between tests rather than a single scheduled appointment, and 36.3% of Superpower members reduced their biological age score between their first and second year.
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What is Superpower, and what is Hone Health?

Superpower and Hone Health are both biomarker testing services. A biomarker testing service measures signals in your blood at set intervals. Biomarkers are things like cholesterol, blood sugar, hormones, and inflammation. Some services stop at a panel and a report. Others turn results into a plan and ongoing care.

Two questions separate them: how much do they measure, and what do they help you do next?

One nuance matters here. Some services test broadly across the whole body, while others go deep on a single area like hormones. Superpower and Hone Health sit on opposite ends of that line.

What does Superpower include?

Superpower follows a simple path:

  1. Join for $349 a year. (HSA/FSA eligible)
  2. Give an initial blood draw at a lab, or at home for an added fee.
  3. Receive ~90 health metrics in your dashboard.
  4. Take a built-in follow-up draw later in the year, retesting ~60 biomarkers.
  5. Get a personalized action plan.
  6. Message your care team on demand.

Testing reaches 2,000+ partner locations across 40+ states. Results arrive in your dashboard 5-10 business days after each draw.

Among those results is a biological-age score, included in every membership. It's a single number for your whole body, so an optional OrganAge add-on breaks it into nine organ-level scores, across systems like metabolism, inflammation, liver, and kidney health, showing you which ones are pulling the total up or down.

You can shop a supplement marketplace with member-exclusive pricing, and prescription access is available in the marketplace (medications priced separately). Gut microbiome testing is an add-on.

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What does Hone Health include?

Hone Health starts with a $65 assessment of 50+ markers, drawn at a national lab location. A board-certified telehealth physician then reviews your results over a video consult and builds a provider-guided treatment plan.

From there you join an ongoing membership, billed monthly from $25 to $155, with retesting cadence that varies by tier. Medication is billed separately.

The real strength here is the clinician model: licensed physicians who specialize in hormone health and prescribe directly. For someone focused on hormone optimization, that's a genuine fit.

What biomarkers do the Superpower and Hone Health memberships measure in 2026?

Superpower's initial draw combines direct lab measurements with calculated, derived metrics for ~90 health metrics; a built-in follow-up draw later in the year retests ~60 of those same markers, for 150+ tests across the two. Hone's panel is smaller and hormone-centric by design.

SuperpowerHone Health
ScopeWhole-bodyHormone-focused
How the headline count is built150+ across an initial ~90-metric draw plus a built-in retest of ~60 of the same markers50+ per panel, retested on a cadence that varies by tier

The difference is breadth versus focus, not one panel measuring more markers than the other. For hormone health, total and free testosterone are the markers commonly assessed when evaluating testosterone, with SHBG, LH, estradiol, and hematocrit for context, per Endocrine Society guidance.

What support and next steps do Superpower and Hone Health offer?

Hone Health has real prescription depth. Its telehealth physicians prescribe TRT for men, HRT for women, GLP-1 medications, and other hormone therapy, with frequent hormone retesting. Here's where the two genuinely differ, and it cuts both ways.

That retesting stays within the same 50+ marker Hone panel, while a Superpower follow-up draw repeats key trackable markers rather than the full initial ~90-marker whole-body panel. If hormone treatment is your main goal, that's a strong, focused offering.

Superpower also includes prescription access when clinically appropriate, covering options like TRT and GLP-1s, priced separately, plus on-demand care-team messaging and a supplement marketplace with member-exclusive pricing. The difference is scope. Hone goes deep on one area; Superpower wraps hormones into a whole-body baseline you can act on across the board.

What are the official 2026 membership prices for Superpower and Hone Health?

Superpower costs $349 a year.

  • Superpower: one flat $349/year membership, HSA/FSA eligible, with no tier-dependent range to calculate.
  • Hone Health: Premium runs $65 to start plus $155 a month, which annualizes to roughly $1,925, with medication billed on top; Basic starts far lower: a $25 initial test plus a one-time $25 onboarding fee, then $25 a month. Against Hone's Premium tier, Superpower is clearly cheaper, but Basic's low monthly fee means its first-year total depends on how many months you stay enrolled, so "Superpower costs less" doesn't hold as a flat claim across every tier.

Who is Superpower best for, and who is Hone Health best for?

Superpower is best for:

  • People who want a full whole-body baseline, not just hormone data.
  • People who want a protocol and care in one membership.
  • Testers who want one predictable flat price ($349) rather than a range that depends on tier and treatment.
  • People who want their whole-body baseline covered by just two built-in draws a year.
  • People who want supplement and prescription access together.

Hone Health is best for:

  • Men, and increasingly women, focused specifically on hormone optimization.
  • People who want provider-guided TRT, HRT, or related treatment.
  • People who value frequent hormone retesting with telehealth physicians.

Test 150+ biomarkers

One membership, two built-in draws. Get a full picture of your health and the action plan you need to improve it.

Book your test

The final word: does Superpower or Hone Health fit you?

Both services start with blood, but they answer different questions. Hone Health goes deep on one area: hormones. That focus is genuine, and for someone whose main goal is TRT or HRT, it fits well.

But hormones are one part of your health, not the whole of it. Metabolic, cardiovascular, thyroid, kidney, liver, and inflammation markers all move on their own timelines, and a hormone-led panel is narrower by design. A fuller baseline is what surfaces the problems you weren't already looking for.

Superpower: whole-body context vs. Hone's hormone-only focus

Hone Health's hormone-only model leaves everything else on you: track hormones with a physician, then go find a separate way to watch your metabolic, cardiovascular, thyroid, kidney, liver, and inflammation markers. Superpower folds all of that into one $349/year membership, an initial complete draw plus a built-in follow-up draw against Hone's $65 assessment plus a $25-$155/month membership. It pairs that with a personalized action plan and on-demand care-team messaging between tests, rather than a single scheduled visit. In Superpower's own member data, 60% of members said Superpower identified something previously missed or overlooked by a doctor.

Starting with the whole picture, rather than one system at a time, is the more useful place to begin a health journey. Start your Superpower blood test and see where your numbers actually stand.

Frequently asked questions

References

  1. Hone Health. (2026). Hone Health: A telehealth clinic unlocking energy and longevity. Hone Health.
  2. Hone Health. (2026). How it works | Hone Health membership process. Hone Health.
  3. Hone Health. (2026). TRT cost per month: How much is testosterone? Hone Health.
  4. Inner Balance. (2026). Hone Health review 2026. Inner Balance.
  5. Bhasin, S., Brito, J. P., Cunningham, G. R., et al. (2018). Testosterone therapy in men with hypogonadism: An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 103(5), 1715-1744.

Put your health in trusted hands

  • Harvard Medical School
  • University of Chicago Pritzker School of Medicine
  • UCLA
  • Tufts School of Medicine
Dr. Anant Vinjamoori

Dr. Anant Vinjamoori, MD

Chief Longevity Officer, Superpower

Dr. Leigh Erin Connealy

Dr. Leigh Erin Connealy, MD

Clinician & Founder of The Centre for New Medicine

Dr. Abe Malkin

Dr. Abe Malkin, MD

Founder & Medical Director of Concierge MD

Dr. Robert Lufkin

Dr. Robert Lufkin, MD

Physician & UCLA Medical School Professor, NYT bestselling author

4.6 out of 5Trustpilot

Transforming 150,000+ lives and counting

Camelia, 29

Camelia, 29

“I left the appointment feeling like I was being dramatic. I wasn't being dramatic. I was being responsible.”

Doctors refused to test her fertility, so she took control of her health

Thach, 37

Thach, 37

“They told me I was overthinking my genetic risk of diabetes but when I tested with Superpower I found my A1c was really high.”

His Superpower test caught diabetes risk that two doctors missed

Carissa, 38

Carissa, 38

“I spent almost a year thinking something was wrong with me. Turns out a simple blood test could have told me in a week.”

Uncovered the hormone imbalances behind bloating and weight gain

Teva, 28 and Cole, 29

Teva, 28 and Cole, 29

“I got my boyfriend a Superpower blood test. And it opened his eyes to things that seriously needed to change.”

The gift that changed how they think and talk about health

Ron, 53

Ron, 53

“I was putting in so much effort to improve my health. But nothing was working, until I got testing that actually showed me what to focus on.”

Superpower gave him a supplement plan that saved him time and money

1 / 5
Biological age 32 — a Superpower member portraitA health system built around you — test, understand, optimize150+ biomarkers across 2 blood drawsWhat to expect with Superpower — week 1 to month 3Trusted by 64,000+ customers — member reviewsBetter than the status quo — Superpower vs the old way60% of members found something a doctor missed — member survey
Daniel OSuperpower memberDavid LSuperpower memberRachel DSuperpower memberCamelia VSuperpower member

4.6 · 64,000+ members

Superpower health membership

Find early signs of 1,000+ conditions - then act, retest, and see what changed.

$349

/year*

150+ biomarkers annually across baseline + retest

Personalized plan that turns results into action

Superpower AI and on-demand care team

Results in 10 days or less

At-home or 2,000+ labs nationwide**

Yearly membership$0.96 / dayHSA/FSA eligible

*Pricing may vary for members in New York and New Jersey

**At-home labs for an additional cost

What we test

TestosteroneFree T4Vitamin DApoBHbA1cThyroid (TSH)hs-CRPFerritinCortisolFasting insulin

60%

found something a doctor missed

93%

rated it more useful than their checkup

77%

found something new in their results

Superpower member survey, 90 days post action plan (n=143).

How does the Superpower membership work?

We test 150+ biomarkers annually across two blood draws. Your baseline test paints a comprehensive picture of your health, and your dashboard shows what’s working, what needs attention, and what to do next. Superpower AI and your care team help you take action across lifestyle, supplements, and treatments. Then we retest to track your progress and continue refining your plan.

Can I cancel anytime?

Yes. You can cancel anytime, no fees. Your membership stays active through the end of your paid year.

How often should I test?

Your membership includes two blood tests per year: one to establish your baseline, and one to see whether your plan improved biomarkers that were out of range or not yet optimized. You can add other diagnostics anytime through the app or with help from your care team.

When will I get my results?

Book your draw at any of 2,000+ partner labs or at-home. Results are typically ready in about a week and land in the Superpower app.

What the 100+ panel measures

All 101 markers in your annual baseline draw, organized by system. Nothing here is an upsell.

Heart & Vascular Health

26

  • Apolipoprotein B
  • Atherogenic Coefficient
  • Atherogenic Index of Plasma
  • Castelli Risk Index I
  • Castelli Risk Index II
  • HDL Cholesterol
  • LDL Cholesterol
  • LDL/HDL Ratio
  • Cholesterol, Total
  • Non-HDL Cholesterol
  • Cholesterol/HDL Ratio
  • Carbon Dioxide, Total
  • High-sensitivity CRP
  • hsCRP-to-Albumin Ratio (CAR)
  • GGT-to-HDL Cholesterol Ratio
  • LDL-C to Apolipoprotein B Ratio (LDL-C/ApoB)
  • LDL Cholesterol / Total Cholesterol (Mass Ratio)
  • Monocyte-to-HDL Ratio (MHR)
  • Neutrophil-to-HDL Cholesterol Ratio (NHR)
  • Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB)
  • NON-HDL Total Cholesterol Ratio
  • Triglyceride HDL Molar Ratio
  • Triglycerides
  • Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB)
  • TyG Index
  • Uric Acid

Metabolic Health

4

  • Estim. Avg Glu (eAG)
  • Eag (mmol/l)
  • Glucose
  • Hemoglobin A1c

Energy

1

  • Cortisol

Liver Health

15

  • Albumin/Globulin Ratio
  • Albumin
  • Alkaline Phosphatase (ALP)
  • Alanine Aminotransferase (ALT)
  • Aspartate Aminotransferase (AST)
  • Bilirubin Direct
  • Bilirubin Indirect
  • Bilirubin, Total
  • Bilirubin-to-Albumin Ratio
  • Ferritin
  • Ferritin-to-Albumin Ratio
  • y-Glutamyl Transferase (GGT)
  • Globulin, Total
  • Indirect-to-Direct Bilirubin Ratio
  • Protein, Total

Kidney

11

  • Calcium
  • Chloride
  • Corrected Calcium (Albumin-adjusted)
  • Creatinine
  • Estimated Glomerular Filtration Rate (eGFR)
  • Potassium
  • Sodium
  • BUN/Creatinine Ratio
  • Blood Urea Nitrogen (BUN)
  • Urea-to-Creatinine Ratio
  • Uric Acid-to-HDL Cholesterol Ratio (UHR)

Sex Hormones

7

  • DHEA-Sulfate (DHEA-S)
  • Free Androgen Index
  • Sex Hormone Binding Globulin (SHBG)
  • Free Testosterone
  • Testosterone, Bioavailable
  • Testosterone, Total
  • Testosterone-to-Estradiol Ratio (T/E₂)

Thyroid Health

4

  • Free Thyroxine Index
  • T3 Uptake
  • T4 (thyroxine) Total
  • Thyroid-Stimulating Hormone (TSH)

Nutrients

13

  • Vitamin D
  • Red Cell Dist Width (RDW)
  • Hematocrit
  • Hemoglobin
  • Total Iron Binding Capacity (TIBC)
  • Iron
  • Iron Saturation
  • Mean Cell Hemoglobin (MCH)
  • Mean Corpuscular Hemoglobin Concentration (MCHC)
  • Mean Cell Volume (MCV)
  • Platelet-to-WBC Ratio (PWR)
  • Red Blood Cells
  • RDW MCV Ratio

Immune System

12

  • Basophils
  • Baso (Absolute)
  • Eosinophils
  • Eos (Absolute)
  • Lymphocytes
  • Lymphs (Absolute)
  • Monocytes
  • Monocytes (Absolute)
  • Neutrophils
  • Neutrophils (Absolute)
  • Mean Platelet Volume
  • Platelet Count

Inflammation

8

  • Lymphocyte-to-Monocyte Ratio (LMR)
  • Monocyte-to-Lymphocyte Ratio (MLR)
  • Neutrophil-to-Lymphocyte-Platelet Ratio (NLPR)
  • Neutrophil-to-Lymphocyte Ratio (NLR)
  • Platelet-to-Lymphocyte Ratio (PLR)
  • Systemic Immune-Inflammation Index
  • Systemic Inflammation Response Index (SIRI)
  • White Blood Cells
Get my health baseline

The full list of 100+ markers and 8 specialty add-ons available at superpower.com/what-we-test.