Superpower vs Empirical Health

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Superpower Logo
Empirical Health
Annual baseline test
150+ biomarkers*
100+ biomarkers (sold as a heart health program)
Testing location
2,000+ partner labs (or at-home draw, paid add-on)
2,000+ lab locations (in-lab draw)
Action plan
Superpower's proprietary action plan
Physician-reviewed action plan
On-demand access to care team
Physician video visits + messaging (included in the $190-$399 price)
Follow-up test
Built-in follow-up draw retesting ~60 biomarkers*, included in the membership
Included on the $399/yr program (retests at 3 and 9 months); not on the $190 panel
Curated supplement marketplace with member-exclusive pricing
Not included
Access to personalized prescription Rx medications
Via primary-care physician (not a discounted Rx marketplace)
Data visualization
iOS/Android app + wearable data
Access to gut microbiome testing
Add-on
Not included
Cost
$349
$190 panel (or $399/yr)
Start testing

*Includes direct laboratory measurements and calculated health metrics. Superpower's 150+ reflects combined tests across an initial draw and a built-in retest of the same markers. Comparison based on publicly available information as of 9/1/2026.

Key takeaway:

Empirical Health pairs a $190-$399 program sold around heart health with an ongoing physician-led primary-care relationship: video visits, prescriptions, and continuous Apple Watch monitoring, included in that price. However, if you're looking for broader whole-body testing bundled with a protocol and a supplement and prescription marketplace in one membership, Superpower is $349 a year and pairs 150+ health metrics across an initial draw and a built-in follow-up draw with a personalized action plan — and 36.3% of Superpower members reduced their biological age score between their first and second year.
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What is Superpower, and what is Empirical Health?

Superpower and Empirical Health are both biomarker testing companies. A biomarker testing company offers blood-based testing on a membership basis, measuring your biomarkers at set intervals. Biomarkers are measurable signals in your blood: things like cholesterol, blood sugar, and inflammation.

Two questions separate these services: how much do they measure, and what do they help you do next? It's worth noting the two answer differently.

Empirical extends into ongoing primary care. Superpower extends into a protocol plus a supplement and prescription marketplace.

What does Superpower include?

Superpower follows a simple path:

  1. Join for $349 a year.
  2. Give an initial blood draw at a lab, or at home for an added fee.
  3. Receive ~90 health metrics in your dashboard.
  4. Take a built-in follow-up draw later in the year, retesting ~60 biomarkers.
  5. Get a personalized action plan.
  6. Message your care team on demand.

Testing reaches 2,000+ partner locations across 40+ states. Results arrive in 5-10 business days. You can shop a supplement marketplace with member-exclusive pricing, and prescriptions are available through the marketplace, when clinically appropriate, priced separately.

Your results include a biological-age score, included in every membership. It's a single number for your whole body, so an optional OrganAge add-on breaks it into nine organ-level scores, across systems like metabolism, inflammation, liver, and kidney health, showing you which ones are pulling the total up or down.

Gut microbiome testing is a separate add-on, for members who want a read on gut health alongside their blood work.

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What does Empirical Health include?

Empirical Health is a physician-led primary-care practice, not just a testing company.

SuperpowerEmpirical Health
Action plan basisAI-generated, physician-reviewed
Wearable integrationConnect your wearables to your dashboardContinuous Apple Watch, Fitbit, and Samsung data (ECG, HRV, sleep) feeding care plans
Results turnaround5-10 business days3-5 business days

What biomarkers do the Superpower and Empirical Health memberships measure in 2026?

Superpower's initial draw runs ~90 biomarkers, with 150+ tests total once its built-in retest of ~60 of them is folded in. Empirical Health publishes 100+ biomarkers on its $190 panel; its $399 program adds repeat testing at 3 and 9 months. The two count on different bases: Superpower's headline is tests returned across two draws, while Empirical's is the markers on a single panel.

  • Headline count — Superpower: 150+ biomarkers*; Empirical Health: 100+ biomarkers
  • Counted from — Superpower: An initial ~90 biomarker draw plus a built-in follow-up draw retesting ~60 of the same markers; Empirical Health: One panel (the $399 program adds repeat testing at 3 and 9 months)
  • Focus — Superpower: Whole-body; Empirical Health: Sold as a heart health program (its published marker list spans more than heart panels)

*Superpower's 150+ combines direct lab measurements with calculated ratios like LMR, MLR, and Ferritin:Albumin.

What support and next steps do Superpower and Empirical Health offer?

Superpower includes on-demand access to a care team you can message about your results, plus a curated supplement marketplace, with prescriptions available through the marketplace when clinically appropriate and priced separately, all in one membership. This is where the two diverge most.

Empirical works differently. Its strength is an ongoing physician relationship included in the price: video visits, referrals, and prescriptions through the practice.

Superpower complements your primary-care doctor rather than replacing one. The trade-off is real: a doctor relationship versus a testing-to-action loop under one roof. What a broad baseline adds alongside either is reach: 60% of members said Superpower identified something previously missed or overlooked by a doctor.

What are the official 2026 membership prices for Superpower and Empirical Health?

Superpower costs $349 a year, billed as a recurring membership.

  • Superpower: $349 a year covers the initial draw and the built-in follow-up draw, and the membership is HSA/FSA eligible.
  • Empirical Health: a $190 one-time panel, or a $399-a-year 12-month heart health program that bundles custom repeat testing at 3 and 9 months; both are HSA/FSA eligible.

The honest read: Empirical's $190 panel is a single snapshot, its $399 program is a year of built-in heart-health retesting, and Superpower's $349 membership is a whole-body annual baseline with a built-in retest of its own — the choice comes down to what you want measured, how often, and what's bundled around it.

Who is Superpower best for, and who is Empirical Health best for?

Superpower is best for:

  • People who want a whole-body baseline rather than a heart-health program.
  • People who want a protocol plus supplements and Rx at member-exclusive pricing in one membership.
  • People who want gut-microbiome or OrganAge add-ons.
  • People optimizing health alongside their existing doctor.

Empirical Health is best for:

  • People who want an ongoing, physician-led primary-care relationship.
  • People whose main focus is cardiovascular risk.
  • People who want continuous Apple Watch monitoring reviewed by a doctor.

Test 150+ biomarkers

One membership, two built-in draws. Get a full picture of your health and the action plan you need to improve it.

Book your test

The final word: does Superpower or Empirical Health fit you?

At different price structures — Superpower's $349 annual membership against Empirical's $190-$399 program — both give a serious baseline. Empirical Health is a genuine physician-led primary-care relationship with Apple Watch monitoring, a real strength if you want an ongoing doctor built into the price.

Superpower's panel spans 150+ whole-body metrics across an initial draw and a built-in follow-up draw, while Empirical Health, including its $399 annual program, is marketed around heart health. Empirical's physician care is included in the $190-$399 price; Superpower's protocol, on-demand care, and marketplace are bundled into the one flat $349-a-year fee. The choice comes down to what you want your baseline to cover: a program sold around your heart, or a broader whole-body baseline you act on yourself.

Superpower: broader whole-body testing bundled with a protocol and marketplace

Empirical sells the relationship: a physician you can see, message, and get prescriptions from, included in the $190-$399 price, with its testing sold as a heart health program. Acting on what it finds happens elsewhere. Superpower sells what comes after the result. One $349-a-year membership folds in a 150+ metric whole-body baseline across two draws, a personalized action plan, on-demand care-team messaging, a member-priced supplement marketplace, and prescription access (GLP-1, TRT, when clinically appropriate) — so the supplement you're told to take and the prescription you're told to fill are in the same place as the number that prompted them.

Starting your own health journey means seeing the full picture before deciding what to act on next. Build your baseline with a Superpower membership and take it from there.

Frequently asked questions

References

  1. Empirical Health. (2026). Comprehensive biomarker testing and pricing. Empirical Health.
  2. Empirical Health. (n.d.). Proactive primary care that scales. Empirical Health.
  3. Empirical Health. (2026). 12-Month Advanced Heart Health Program. Empirical Health.
  4. 9to5Mac. (2024, July 2). Empirical Health for Apple Watch now leverages AI with your data and real physicians. 9to5Mac.

Put your health in trusted hands

  • Harvard Medical School
  • University of Chicago Pritzker School of Medicine
  • UCLA
  • Tufts School of Medicine
Dr. Anant Vinjamoori

Dr. Anant Vinjamoori, MD

Chief Longevity Officer, Superpower

Dr. Leigh Erin Connealy

Dr. Leigh Erin Connealy, MD

Clinician & Founder of The Centre for New Medicine

Dr. Abe Malkin

Dr. Abe Malkin, MD

Founder & Medical Director of Concierge MD

Dr. Robert Lufkin

Dr. Robert Lufkin, MD

Physician & UCLA Medical School Professor, NYT bestselling author

4.6 out of 5Trustpilot

Transforming 150,000+ lives and counting

Camelia, 29

Camelia, 29

“I left the appointment feeling like I was being dramatic. I wasn't being dramatic. I was being responsible.”

Doctors refused to test her fertility, so she took control of her health

Thach, 37

Thach, 37

“They told me I was overthinking my genetic risk of diabetes but when I tested with Superpower I found my A1c was really high.”

His Superpower test caught diabetes risk that two doctors missed

Carissa, 38

Carissa, 38

“I spent almost a year thinking something was wrong with me. Turns out a simple blood test could have told me in a week.”

Uncovered the hormone imbalances behind bloating and weight gain

Teva, 28 and Cole, 29

Teva, 28 and Cole, 29

“I got my boyfriend a Superpower blood test. And it opened his eyes to things that seriously needed to change.”

The gift that changed how they think and talk about health

Ron, 53

Ron, 53

“I was putting in so much effort to improve my health. But nothing was working, until I got testing that actually showed me what to focus on.”

Superpower gave him a supplement plan that saved him time and money

1 / 5
Biological age 32 — a Superpower member portraitA health system built around you — test, understand, optimize150+ biomarkers across 2 blood drawsWhat to expect with Superpower — week 1 to month 3Trusted by 64,000+ customers — member reviewsBetter than the status quo — Superpower vs the old way60% of members found something a doctor missed — member survey
Daniel OSuperpower memberDavid LSuperpower memberRachel DSuperpower memberCamelia VSuperpower member

4.6 · 64,000+ members

Superpower health membership

Find early signs of 1,000+ conditions - then act, retest, and see what changed.

$349

/year*

150+ biomarkers annually across baseline + retest

Personalized plan that turns results into action

Superpower AI and on-demand care team

Results in 10 days or less

At-home or 2,000+ labs nationwide**

Yearly membership$0.96 / dayHSA/FSA eligible

*Pricing may vary for members in New York and New Jersey

**At-home labs for an additional cost

What we test

TestosteroneFree T4Vitamin DApoBHbA1cThyroid (TSH)hs-CRPFerritinCortisolFasting insulin

60%

found something a doctor missed

93%

rated it more useful than their checkup

77%

found something new in their results

Superpower member survey, 90 days post action plan (n=143).

How does the Superpower membership work?

We test 150+ biomarkers annually across two blood draws. Your baseline test paints a comprehensive picture of your health, and your dashboard shows what’s working, what needs attention, and what to do next. Superpower AI and your care team help you take action across lifestyle, supplements, and treatments. Then we retest to track your progress and continue refining your plan.

Can I cancel anytime?

Yes. You can cancel anytime, no fees. Your membership stays active through the end of your paid year.

How often should I test?

Your membership includes two blood tests per year: one to establish your baseline, and one to see whether your plan improved biomarkers that were out of range or not yet optimized. You can add other diagnostics anytime through the app or with help from your care team.

When will I get my results?

Book your draw at any of 2,000+ partner labs or at-home. Results are typically ready in about a week and land in the Superpower app.

What the 100+ panel measures

All 101 markers in your annual baseline draw, organized by system. Nothing here is an upsell.

Heart & Vascular Health

26

  • Apolipoprotein B
  • Atherogenic Coefficient
  • Atherogenic Index of Plasma
  • Castelli Risk Index I
  • Castelli Risk Index II
  • HDL Cholesterol
  • LDL Cholesterol
  • LDL/HDL Ratio
  • Cholesterol, Total
  • Non-HDL Cholesterol
  • Cholesterol/HDL Ratio
  • Carbon Dioxide, Total
  • High-sensitivity CRP
  • hsCRP-to-Albumin Ratio (CAR)
  • GGT-to-HDL Cholesterol Ratio
  • LDL-C to Apolipoprotein B Ratio (LDL-C/ApoB)
  • LDL Cholesterol / Total Cholesterol (Mass Ratio)
  • Monocyte-to-HDL Ratio (MHR)
  • Neutrophil-to-HDL Cholesterol Ratio (NHR)
  • Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB)
  • NON-HDL Total Cholesterol Ratio
  • Triglyceride HDL Molar Ratio
  • Triglycerides
  • Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB)
  • TyG Index
  • Uric Acid

Metabolic Health

4

  • Estim. Avg Glu (eAG)
  • Eag (mmol/l)
  • Glucose
  • Hemoglobin A1c

Energy

1

  • Cortisol

Liver Health

15

  • Albumin/Globulin Ratio
  • Albumin
  • Alkaline Phosphatase (ALP)
  • Alanine Aminotransferase (ALT)
  • Aspartate Aminotransferase (AST)
  • Bilirubin Direct
  • Bilirubin Indirect
  • Bilirubin, Total
  • Bilirubin-to-Albumin Ratio
  • Ferritin
  • Ferritin-to-Albumin Ratio
  • y-Glutamyl Transferase (GGT)
  • Globulin, Total
  • Indirect-to-Direct Bilirubin Ratio
  • Protein, Total

Kidney

11

  • Calcium
  • Chloride
  • Corrected Calcium (Albumin-adjusted)
  • Creatinine
  • Estimated Glomerular Filtration Rate (eGFR)
  • Potassium
  • Sodium
  • BUN/Creatinine Ratio
  • Blood Urea Nitrogen (BUN)
  • Urea-to-Creatinine Ratio
  • Uric Acid-to-HDL Cholesterol Ratio (UHR)

Sex Hormones

7

  • DHEA-Sulfate (DHEA-S)
  • Free Androgen Index
  • Sex Hormone Binding Globulin (SHBG)
  • Free Testosterone
  • Testosterone, Bioavailable
  • Testosterone, Total
  • Testosterone-to-Estradiol Ratio (T/E₂)

Thyroid Health

4

  • Free Thyroxine Index
  • T3 Uptake
  • T4 (thyroxine) Total
  • Thyroid-Stimulating Hormone (TSH)

Nutrients

13

  • Vitamin D
  • Red Cell Dist Width (RDW)
  • Hematocrit
  • Hemoglobin
  • Total Iron Binding Capacity (TIBC)
  • Iron
  • Iron Saturation
  • Mean Cell Hemoglobin (MCH)
  • Mean Corpuscular Hemoglobin Concentration (MCHC)
  • Mean Cell Volume (MCV)
  • Platelet-to-WBC Ratio (PWR)
  • Red Blood Cells
  • RDW MCV Ratio

Immune System

12

  • Basophils
  • Baso (Absolute)
  • Eosinophils
  • Eos (Absolute)
  • Lymphocytes
  • Lymphs (Absolute)
  • Monocytes
  • Monocytes (Absolute)
  • Neutrophils
  • Neutrophils (Absolute)
  • Mean Platelet Volume
  • Platelet Count

Inflammation

8

  • Lymphocyte-to-Monocyte Ratio (LMR)
  • Monocyte-to-Lymphocyte Ratio (MLR)
  • Neutrophil-to-Lymphocyte-Platelet Ratio (NLPR)
  • Neutrophil-to-Lymphocyte Ratio (NLR)
  • Platelet-to-Lymphocyte Ratio (PLR)
  • Systemic Immune-Inflammation Index
  • Systemic Inflammation Response Index (SIRI)
  • White Blood Cells
Get my health baseline

The full list of 100+ markers and 8 specialty add-ons available at superpower.com/what-we-test.