Superpower vs SiPhox Health

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Superpower Logo
SiPhox Health
Annual baseline test
150+ biomarkers*
Up to 59 on its Ultimate 360 panel
Testing location
2,000+ partner labs (or at-home draw, paid add-on)
At-home only: needle-free EasyDraw capillary collection (no lab/venous option)
Action plan
Superpower's proprietary action plan
AI-generated insights and action plan plus supplement recommendations
On-demand access to care team
AI assistant (Sai); human coaching is a paid add-on
Follow-up test
Built-in follow-up draw retesting ~60 biomarkers*, included, once/yr
Flexible retests: monthly, quarterly, or 6-month, change anytime
Curated supplement marketplace with member-exclusive pricing
Recommendations only
Access to personalized prescription Rx medications
Not included
Data visualization
Access to gut microbiome testing
Add-on
Advanced Gut Health add-on
Cost
$349
From $125
Start testing

*Includes direct laboratory measurements and calculated health metrics; 150+ reflects combined tests across an initial draw and a built-in retest of the same markers. Comparison based on publicly available information as of 9/1/2026.

Key takeaway:

SiPhox Health is a needle-free, at-home biomarker service: capillary collection with its EasyDraw device, membership from $125 per testing period, and flexible monthly, quarterly, or biannual retesting across a panel of 29 biomarkers on Longevity Essentials up to 59 on Ultimate 360. However, if you're looking for a fuller venous baseline with more post-testing actionable support, Superpower is $349/year and tests 150+ whole-body health metrics across an initial ~90 biomarker draw plus a built-in follow-up that retests ~60 of them, pairing a personalized action plan with on-demand care-team messaging between tests rather than a single scheduled appointment, and 36.3% of Superpower members reduced their biological age score between their first and second year.
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What is Superpower, and what is SiPhox Health?

Superpower and SiPhox Health are both biomarker testing companies. A biomarker testing company offers blood-based testing on a periodic basis. Biomarkers are measurable signals in your blood, things like cholesterol, blood sugar, and hormones.

Some platforms stop at data and a report. Others turn results into a plan you can act on. Two questions separate them: how much do they measure, and what do they help you do next?

Superpower and SiPhox answer those differently. One is a full membership with care built in; the other is a convenient self-serve tracker whose cost scales with how often you test.

What does Superpower include?

Superpower includes a full annual membership, from an initial venous draw through on-demand care-team access. Superpower follows a simple path:

  1. Join for $349 a year.
  2. Give your initial venous blood draw at a lab, or at home for an added fee.
  3. Receive ~90 health metrics in your dashboard.
  4. Get a personalized action plan.
  5. Give a built-in follow-up draw later, retesting ~60 biomarkers.
  6. Message your care team on demand.

Both draws happen at any of 2,000+ partner locations across 40+ states, or at home for an added fee. Results arrive in your dashboard 5 to 10 business days after each one.

Among those results is a biological-age score, included in every membership. It's a single number for your whole body, so an optional OrganAge add-on breaks it into nine organ-level scores, across systems like metabolism, inflammation, liver, and kidney health, showing you which ones are pulling the total up or down.

You can shop a supplement marketplace with member-exclusive pricing, and prescriptions are available through the marketplace, when clinically appropriate, priced separately.

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What does SiPhox Health include?

SiPhox Health includes an at-home kit with needle-free capillary collection, processed through a CLIA-certified lab. SiPhox is built for convenience. You order a kit, collect a sample at home with its needle-free EasyDraw upper-arm device, then mail it to a CLIA-certified lab. There's no vein draw and no lab visit, which is its genuine edge.

Results come back in 7 to 10 days, paired with AI-generated insights and supplement recommendations. Its broadest tier, Ultimate 360, runs 59 biomarkers, against 29 on Longevity Essentials, and you can retest monthly, quarterly, or every six months. Human coaching is an optional paid add-on, not an included care team.

What biomarkers do the Superpower and SiPhox Health memberships measure in 2026?

Superpower reports 150+ tests across two draws — ~90 from an initial venous draw, plus a built-in follow-up retesting ~60 of those markers — while SiPhox Health measures 29 biomarkers on Longevity Essentials up to 59 on Ultimate 360 per at-home capillary kit. The two count on different bases. Superpower's headline is a two-draw total; SiPhox's is the size of a single panel. In both, repeat testing re-runs markers already on the panel rather than adding new ones.

SuperpowerSiPhox Health
Counted fromInitial venous draw of ~90 biomarkers, plus a built-in follow-up that retests ~60 of those same markersOne at-home capillary kit: 29 biomarkers on Longevity Essentials up to 59 on Ultimate 360, with retests repeating that same panel
Accuracy vs. venousVenous draw is the reference standardCorrelates well with venous methods for markers like HbA1c, glucose, and CRP, but research has found weaker correlation for some lipids

*Superpower's 150+ combines direct lab measurements with calculated metrics like LMR, MLR, and Ferritin:Albumin, spanning an initial draw and a built-in follow-up retest of the same markers. Both run through CLIA-certified labs.

What support and next steps do Superpower and SiPhox Health offer?

This is where the two diverge most. Superpower includes on-demand access to a care team you can message about your results, plus prescriptions are available through the marketplace, when clinically appropriate, priced separately, including TRT. A curated supplement marketplace offers member-exclusive pricing.

SiPhox works differently. It gives you AI-generated insights and supplement recommendations, with human coaching as a paid add-on. There's no included clinician care team, and no prescription access.

SiPhox hands you data and suggestions; Superpower keeps testing and action under one roof. 93% of members rated their Superpower Health Action Plan as more useful or even life-changing compared to their yearly checkup.

What are the official 2026 membership prices for Superpower and SiPhox Health?

SiPhox can cost less at entry, with membership starting at $125 per testing period for one of four core panels.

Who is Superpower best for, and who is SiPhox Health best for?

Superpower is best for:

  • People who want a full venous baseline of ~90 health metrics, 150+ tests across two draws.
  • People who want a protocol and on-demand care, not just data.
  • People who want supplement and prescription access in one place.
  • People who want their biological age broken out organ by organ.

SiPhox Health is best for:

  • Budget self-trackers who want frequent at-home panels.
  • People who want needle-free home collection with no lab visit.
  • People who mainly want data and trend tracking over guidance.

Test 150+ biomarkers

Two draws included. Get a full picture of your health and the action plan you need to improve it.

Book your test

The final word: does Superpower or SiPhox Health fit you?

SiPhox Health wins on entry convenience: needle-free at-home collection with flexible retesting, from $125 per testing period. If low-friction data tracking is all you want, it delivers.

But it stops there, at data and recommendations, and the needle-free format comes with a trade-off. SiPhox's broadest panel runs 59 biomarkers, against ~90 on Superpower's initial venous draw, and capillary samples correlate less well with venous methods for some lipids. Convenience answers what your numbers are; turning that into a next step is left to you.

Superpower: a fuller panel and built-in care vs. SiPhox's needle-free convenience

SiPhox Health's needle-free convenience leaves the next step up to you: track your numbers over time, then decide on your own what to do about a marker that moved or an insight its AI flagged. Superpower folds testing and action into one $349/year membership: ~90 health metrics from an initial venous draw, plus a built-in follow-up retesting ~60 of those same markers, 150+ tests across the two. Each round lands with a personalized action plan, and on-demand care-team messaging carries you between them. SiPhox's $125-per-testing-period model gives you the numbers and the recommendations, then leaves the deciding to you.

Starting with a full picture, not just a single data point, is the better place to begin a health journey. Start your Superpower blood test and see where your numbers actually stand.

Frequently asked questions

References

  1. SiPhox Health. (2026). How much does SiPhox Health cost? SiPhox Health.
  2. SiPhox Health. (2026). Programs and pricing. SiPhox Health.
  3. SiPhox Health. (2026). How it works. SiPhox Health.
  4. SiPhox Health. (2026). At-home blood testing and personalized action plan. SiPhox Health.
  5. OptimizeBiomarkers. (2026). SiPhox Health review 2026. OptimizeBiomarkers.
  6. Lacher, D. A., et al. (2013). Comparison of dried blood spot to venous methods for hemoglobin A1c, glucose, total cholesterol, HDL cholesterol, and C-reactive protein. PubMed.
  7. Crimmins, E., Kim, J. K., McCreath, H., & Faul, J. (2014). Validation of blood-based assays using dried blood spots for use in large population studies. Biodemography and Social Biology. PubMed.

Put your health in trusted hands

  • Harvard Medical School
  • University of Chicago Pritzker School of Medicine
  • UCLA
  • Tufts School of Medicine
Dr. Anant Vinjamoori

Dr. Anant Vinjamoori, MD

Chief Longevity Officer, Superpower

Dr. Leigh Erin Connealy

Dr. Leigh Erin Connealy, MD

Clinician & Founder of The Centre for New Medicine

Dr. Abe Malkin

Dr. Abe Malkin, MD

Founder & Medical Director of Concierge MD

Dr. Robert Lufkin

Dr. Robert Lufkin, MD

Physician & UCLA Medical School Professor, NYT bestselling author

4.6 out of 5Trustpilot

Transforming 150,000+ lives and counting

Camelia, 29

Camelia, 29

“I left the appointment feeling like I was being dramatic. I wasn't being dramatic. I was being responsible.”

Doctors refused to test her fertility, so she took control of her health

Thach, 37

Thach, 37

“They told me I was overthinking my genetic risk of diabetes but when I tested with Superpower I found my A1c was really high.”

His Superpower test caught diabetes risk that two doctors missed

Carissa, 38

Carissa, 38

“I spent almost a year thinking something was wrong with me. Turns out a simple blood test could have told me in a week.”

Uncovered the hormone imbalances behind bloating and weight gain

Teva, 28 and Cole, 29

Teva, 28 and Cole, 29

“I got my boyfriend a Superpower blood test. And it opened his eyes to things that seriously needed to change.”

The gift that changed how they think and talk about health

Ron, 53

Ron, 53

“I was putting in so much effort to improve my health. But nothing was working, until I got testing that actually showed me what to focus on.”

Superpower gave him a supplement plan that saved him time and money

1 / 5
Biological age 32 — a Superpower member portraitA health system built around you — test, understand, optimize150+ biomarkers across 2 blood drawsWhat to expect with Superpower — week 1 to month 3Trusted by 64,000+ customers — member reviewsBetter than the status quo — Superpower vs the old way60% of members found something a doctor missed — member survey
Daniel OSuperpower memberDavid LSuperpower memberRachel DSuperpower memberCamelia VSuperpower member

4.6 · 64,000+ members

Superpower health membership

Find early signs of 1,000+ conditions - then act, retest, and see what changed.

$349

/year*

150+ biomarkers annually across baseline + retest

Personalized plan that turns results into action

Superpower AI and on-demand care team

Results in 10 days or less

At-home or 2,000+ labs nationwide**

Yearly membership$0.96 / dayHSA/FSA eligible

*Pricing may vary for members in New York and New Jersey

**At-home labs for an additional cost

What we test

TestosteroneFree T4Vitamin DApoBHbA1cThyroid (TSH)hs-CRPFerritinCortisolFasting insulin

60%

found something a doctor missed

93%

rated it more useful than their checkup

77%

found something new in their results

Superpower member survey, 90 days post action plan (n=143).

How does the Superpower membership work?

We test 150+ biomarkers annually across two blood draws. Your baseline test paints a comprehensive picture of your health, and your dashboard shows what’s working, what needs attention, and what to do next. Superpower AI and your care team help you take action across lifestyle, supplements, and treatments. Then we retest to track your progress and continue refining your plan.

Can I cancel anytime?

Yes. You can cancel anytime, no fees. Your membership stays active through the end of your paid year.

How often should I test?

Your membership includes two blood tests per year: one to establish your baseline, and one to see whether your plan improved biomarkers that were out of range or not yet optimized. You can add other diagnostics anytime through the app or with help from your care team.

When will I get my results?

Book your draw at any of 2,000+ partner labs or at-home. Results are typically ready in about a week and land in the Superpower app.

What the 100+ panel measures

All 101 markers in your annual baseline draw, organized by system. Nothing here is an upsell.

Heart & Vascular Health

26

  • Apolipoprotein B
  • Atherogenic Coefficient
  • Atherogenic Index of Plasma
  • Castelli Risk Index I
  • Castelli Risk Index II
  • HDL Cholesterol
  • LDL Cholesterol
  • LDL/HDL Ratio
  • Cholesterol, Total
  • Non-HDL Cholesterol
  • Cholesterol/HDL Ratio
  • Carbon Dioxide, Total
  • High-sensitivity CRP
  • hsCRP-to-Albumin Ratio (CAR)
  • GGT-to-HDL Cholesterol Ratio
  • LDL-C to Apolipoprotein B Ratio (LDL-C/ApoB)
  • LDL Cholesterol / Total Cholesterol (Mass Ratio)
  • Monocyte-to-HDL Ratio (MHR)
  • Neutrophil-to-HDL Cholesterol Ratio (NHR)
  • Non-HDL Cholesterol-to-Apolipoprotein B Ratio (Non-HDL-C/ApoB)
  • NON-HDL Total Cholesterol Ratio
  • Triglyceride HDL Molar Ratio
  • Triglycerides
  • Triglyceride-to-Apolipoprotein B Ratio (TG/ApoB)
  • TyG Index
  • Uric Acid

Metabolic Health

4

  • Estim. Avg Glu (eAG)
  • Eag (mmol/l)
  • Glucose
  • Hemoglobin A1c

Energy

1

  • Cortisol

Liver Health

15

  • Albumin/Globulin Ratio
  • Albumin
  • Alkaline Phosphatase (ALP)
  • Alanine Aminotransferase (ALT)
  • Aspartate Aminotransferase (AST)
  • Bilirubin Direct
  • Bilirubin Indirect
  • Bilirubin, Total
  • Bilirubin-to-Albumin Ratio
  • Ferritin
  • Ferritin-to-Albumin Ratio
  • y-Glutamyl Transferase (GGT)
  • Globulin, Total
  • Indirect-to-Direct Bilirubin Ratio
  • Protein, Total

Kidney

11

  • Calcium
  • Chloride
  • Corrected Calcium (Albumin-adjusted)
  • Creatinine
  • Estimated Glomerular Filtration Rate (eGFR)
  • Potassium
  • Sodium
  • BUN/Creatinine Ratio
  • Blood Urea Nitrogen (BUN)
  • Urea-to-Creatinine Ratio
  • Uric Acid-to-HDL Cholesterol Ratio (UHR)

Sex Hormones

7

  • DHEA-Sulfate (DHEA-S)
  • Free Androgen Index
  • Sex Hormone Binding Globulin (SHBG)
  • Free Testosterone
  • Testosterone, Bioavailable
  • Testosterone, Total
  • Testosterone-to-Estradiol Ratio (T/E₂)

Thyroid Health

4

  • Free Thyroxine Index
  • T3 Uptake
  • T4 (thyroxine) Total
  • Thyroid-Stimulating Hormone (TSH)

Nutrients

13

  • Vitamin D
  • Red Cell Dist Width (RDW)
  • Hematocrit
  • Hemoglobin
  • Total Iron Binding Capacity (TIBC)
  • Iron
  • Iron Saturation
  • Mean Cell Hemoglobin (MCH)
  • Mean Corpuscular Hemoglobin Concentration (MCHC)
  • Mean Cell Volume (MCV)
  • Platelet-to-WBC Ratio (PWR)
  • Red Blood Cells
  • RDW MCV Ratio

Immune System

12

  • Basophils
  • Baso (Absolute)
  • Eosinophils
  • Eos (Absolute)
  • Lymphocytes
  • Lymphs (Absolute)
  • Monocytes
  • Monocytes (Absolute)
  • Neutrophils
  • Neutrophils (Absolute)
  • Mean Platelet Volume
  • Platelet Count

Inflammation

8

  • Lymphocyte-to-Monocyte Ratio (LMR)
  • Monocyte-to-Lymphocyte Ratio (MLR)
  • Neutrophil-to-Lymphocyte-Platelet Ratio (NLPR)
  • Neutrophil-to-Lymphocyte Ratio (NLR)
  • Platelet-to-Lymphocyte Ratio (PLR)
  • Systemic Immune-Inflammation Index
  • Systemic Inflammation Response Index (SIRI)
  • White Blood Cells
Get my health baseline

The full list of 100+ markers and 8 specialty add-ons available at superpower.com/what-we-test.