Mito Health vs OneTwenty

What is Mito Health, and what is OneTwenty?

Mito Health runs on a simple pitch: "We profit from membership, not from your tests." The membership costs $99 a year, and the tests it unlocks are priced at what Mito pays to provide them.

OneTwenty describes "a health optimization membership, not a medical practice." One annual fee covers a 101-marker baseline and a retest every quarter. OneTwenty is still accepting founding members ahead of its public launch.

Mito hands you a catalog and lets you decide what to test. OneTwenty decides the schedule for you, and it sells supplements and medications that Mito has not launched yet.

What does Mito Health include?

Membership at Mito Health buys three things: member pricing on every test, a clinician-reviewed action plan with trend and biological age tracking, and the Mito Concierge AI assistant. The tests themselves cost extra.

Mito publishes a five-step process:

1. Choose and order your tests — Shop a catalog of 1,000+ labs, scans, kits, and panels, priced at cost for members.
2. Fill in your health profile — Add your concerns, habits, family history, and past lab reports.
3. Provide your sample — Take a lab visit, an at-home draw, or an at-home kit you mail back.
4. Get clinician-reviewed results — Clinicians go over each result and post insights in your dashboard, and members can reach the care team.
5. Retest with focus — Targeted panels follow what changed and what still needs a closer look.

Members can also add a live 1:1 consult with the care team for $39 per 30 minutes.

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What does OneTwenty include?

With OneTwenty you get quarterly draws, a health coach, an AI health assistant, and device syncing, while supplement packs and medications cost extra.

The company lists five steps:

1. Sign up — One annual membership at founding-member pricing.
2. Schedule labs — Walk in at no extra cost, or pay for a phlebotomist at your door, while an independent licensed provider orders the panel.
3. Connect devices and past labs — Add wearables and any lab results you already hold.
4. Results plus action plan — Markers are explained, and a protocol follows.
5. Retest quarterly — Focused panels every 90 days track the markers that need watching.

Results arrive in about a week, and the AI assistant watches incoming device data between draws.

What biomarkers do Mito Health and OneTwenty measure in 2026?

Mito Health's curated line has four panels, from Essential at 117 biomarkers through Core at 139 and Pro at 167 up to Ultra at 182, while OneTwenty's baseline holds 101 markers.

The table sets OneTwenty's baseline beside Mito Core, which Mito calls its most popular panel. Both counts include urinalysis and calculated values.

One Mito Core draw lists more markers than OneTwenty's baseline. OneTwenty's quarterly panels add three more draws of 20 to 40 markers each.

Mito's catalog stretches well past blood work:

• Curated panels — Essential, Core, Pro, and Ultra, the last adding Galleri and an at-home gut test.
• Scans and fitness tests — DEXA, coronary artery calcium, VO2 max, and a Prenuvo whole-body MRI.
• At-home kits — Blood collection kits, gut microbiome analysis, H. pylori breath testing, and whole-genome sequencing.

OneTwenty's extras are tied to the retest loop:

• Quarterly panels — 20 to 40 markers each, chosen from your baseline and included in the membership.
• Device metrics — 22 readings streaming from your wearables, kept apart from lab results.
• Prescription markers — If a provider prescribes something, the markers it affects join your next quarterly panel. OneTwenty has no separate catalog of tests or scans.

What are the official 2026 membership prices for Mito Health and OneTwenty?

Mito Health costs $99 a year, or $9 a month, with every test priced on top. OneTwenty's $499 a year is a founding-member rate that ends at public launch.

Core, Mito's most popular panel, is $197.59 at member pricing. Essential is $89.60, Pro is $323.88, and Ultra is $1,503.45, all before the $15 draw fee. Adding the $99 membership, the $197.59 Core panel, and a $15 draw fee comes to $311.59 for a year, and a second draw with Essential plus another draw fee brings it to $416.19. Both years cost less than OneTwenty's founding price, though OneTwenty's includes four draws.

New York and New Jersey change both sides. Mito builds state fees into each test's price, about 133% higher, while OneTwenty charges $749 for the same four panels, with at-home draws required.

Both are HSA/FSA eligible. OneTwenty labels its membership reimbursement eligible, and its FAQ says the final answer rests with your specific plan.

How do supplements and prescriptions differ?

OneTwenty sells supplements and prescriptions today, and Mito Health lists both as planned.

Mito's manifesto calls supplements and prescriptions "coming soon, priced the same way" as its tests. Neither is on sale today. Mito's action plans still cover supplements, exercise, nutrition, and sleep, and Mito Concierge answers questions about them.

OneTwenty's Custom Packs are one daily supplement pack built from your latest panel, from $67 a month, re-formulated every quarter. Medications and hormone therapy run through independent licensed providers, from $49 a month. The brand puts lifestyle first and supplements second, with medication only if your data and a provider support it.

Both add-ons bill on top of the OneTwenty membership.

How does the testing model differ?

Mito Health lets you pick every test, while OneTwenty sets a baseline and a quarterly cadence for you.

Mito's catalog suits people who already know what to measure, and Concierge will assemble a custom panel or schedule the lab visit if you ask. A retest means buying the next panel.

OneTwenty picks the retest for you. Its three quarterly panels target the markers that need watching, so the second, third, and fourth draws shrink to 20 to 40 markers each. The membership price covers them.

Collection differs too. Mito's at-home draw costs $99 per visit in 35 states, and OneTwenty's costs $99 per visit, with a free walk-in alternative. OneTwenty itself operates in 49 states, leaving out only Rhode Island.

How do care and results timing compare?

Mito Health adds a clinician review and an optional consult, while OneTwenty relies on a coach and independent providers.

Each Mito result goes to a clinician for review before the analysis and plan are final. Concierge texts the care team when a question needs clinical input. Mito says to expect results 7 to 10 days after the lab visit. The care team's review lands roughly 2 weeks after the first results.

At OneTwenty, a dedicated coach walks you through results and independent providers handle anything clinical. The dashboard boils labs and device data down to a 0 to 100 One Health Score, which OneTwenty bases on the American Heart Association's Life's Essential 8. Biological age sits apart, in a free calculator on OneTwenty's website.

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Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

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Who is Mito Health best for, and who is OneTwenty best for?

Mito Health is best for:

• People who already know which tests to order and want them at cost.
• People who want scans, kits, and specialty panels in one catalog.
• People who want the option of a live consult with the care team.

OneTwenty is best for:

• People who want four draws a year without ordering each one.
• People who want a coach and device data alongside their labs.
• People who want supplements and medications available today and can accept founding-member terms.

The bottom line

Mito Health fits people who want to choose their own tests and pay cost for them. OneTwenty fits people who want a set rhythm of four draws, a coach, and supplement and medication options available now.

Both models stop at different points. Mito still lists supplements and prescriptions as coming soon, and OneTwenty's extra markers come only through its quarterly retests, with packs from $67 a month and medications from $49 above its $499 founding-member price.

Superpower costs $199 a year in most states, below both the $311.59 Mito year with one Core panel and OneTwenty's $499 founding-member price. Wearable data, medical records, and the results of one 100+ biomarker draw feed one Superpower AI that writes your Superpower Protocol. Beside add-on tests and scans, the marketplace lists supplements at up to 20% off, with prescriptions available when clinically appropriate, priced separately. 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.