Which costs less, Empirical Health or Hone Health?

Empirical Health costs less up front at $190 once. Hone's Basic plan is $25 a month, which is $300 a year before medication, and Premium is $155 a month, or $1,860 a year before medication. Empirical's $399 Advanced program, which includes a doctor visit, falls between the two Hone tiers.

Can Empirical Health or Hone Health prescribe medication?

Both can. Empirical covers prescriptions and referrals during the video visit in its $399 Advanced program. Hone makes prescriptions core to its plans, in categories such as low testosterone, thyroid, and menopause, with medication priced on top of the membership. Basic does not include hormone therapy.

Does Hone Health test more biomarkers than Empirical Health?

Not on a like-for-like basis. Empirical lists 85 lab results, but 26 are urinalysis items, and Hone's 63 listed blood markers carry none, so the blood-only counts sit at 59 and 63. Hone retests every 3 months on Premium and every 6 on Basic, so it can run more draws over a year.

How fast do Empirical Health and Hone Health results arrive?

At Empirical, most results arrive in 3 to 5 business days, and the full set takes two to three weeks. Hone's lab-processed results take about 10 business days, followed by a physician review within 1 to 2 business days. At-home kits take about 4 business days after the lab receives them.

Do Empirical Health or Hone Health sell supplements?

Hone does, through its own storefront of nine supplements priced from $25 to $80. Empirical does not offer supplements.

Are Empirical Health and Hone Health HSA/FSA eligible?

Yes, subject to your plan. Empirical's heart health program is HSA/FSA eligible, and Hone says eligibility depends on your plan and supplies a receipt you can file. Plan administrators set their own vendor restrictions.

Empirical Health vs Hone Health: Features & Pricing (2026)

Key takeaway:

Empirical Health ($190 one-time) is a heart health company, reading 100+ biomarkers in one lab visit and adding a doctor video visit at $399. Hone Health (Premium $155/mo plus medication) is an online clinic where physician consults and prescriptions sit at the center of the plan. If you want more than a heart panel or a clinic plan, Superpower ($199/yr) goes beyond biomarker testing to be a true home for health. One flat price includes 100+ biomarkers from one draw, and Superpower AI builds a full action plan from your data.

What is Empirical Health, and what is Hone Health?

Empirical Health focuses on the heart. You buy a $190 panel once, read 100+ biomarkers through an app, and see what they imply for cardiovascular risk.

Hone Health calls itself an online clinic. Lab work is the front door to a monthly plan, where physicians guide your care and ship prescribed medication to your home.

The tests are the main event at one company and the intake step at the other, which shapes every price and feature below.

What does Empirical Health include?

A $190 purchase gets you a lab visit, 100+ biomarkers, app-based heart risk scores, and Empirical Pro.

Empirical frames the experience in three steps:

Measure — Stop by a testing site for your draw, which covers ApoB and Lp(a).
Predict — Watch your 10-year and lifetime heart-disease risk shift as you try lifestyle changes.
Prevent — Receive a nutrition and exercise plan, and photograph meals to log them.

A physician-interpreted report comes with the results. For $399, the Advanced Heart Health program stretches over 12 months, with draws at months 3 and 9 and a visit with a board-certified doctor.

What does Hone Health include?

Hone's Premium plan includes 50+ lab tests, physician consults, unlimited messaging with a care team, and access to prescribed medication and supplements.

Hone describes Premium in four steps:

Measure what matters — Book a comprehensive panel at a partner lab.
Consult with a licensed physician — Go over labs, symptoms, history, and goals on a private video call.
Ongoing personalized care — Get retesting and clinician support, plus medication and supplements.
Optimize your health — Retest and meet your clinician every 3 months.

Basic is the lighter tier. It has no included consult, retests every 6 months, and lets you book a physician for $75 (men) or $100 (women). A third tier, Plus, is a men's hormone therapy program built on a separate at-home kit. Care comes from Hone-affiliated practices owned by licensed physicians.

What biomarkers do Empirical Health and Hone Health measure in 2026?

Empirical publishes 100+ biomarkers from one draw, and Hone publishes 50+ lab tests per panel, though its list names 63 across men and women.

	Empirical Health	Hone Health
Initial draw	85 lab biomarkers (72 distinct and 13 calculated)	63 biomarkers listed across both sexes (51 distinct and 12 calculated)
Follow-up draw	Repeat testing at 3 and 9 months in the $399 program	Retest every 3 months on Premium, every 6 on Basic
Headline count	100+ biomarkers	50+ lab tests

Both lists carry ApoB. Hone's comprehensive panel groups its tests into thyroid, sex hormones, complete blood count, lipids, and a metabolic panel, and the men's version adds PSA while the women's adds FSH, progesterone, and TPO. Empirical's 85 lab results lean toward heart and metabolic markers.

Each sells a step beyond its base test:

Empirical Health — The Advanced program adds repeat draws and the doctor visit.
Hone Health — Plus adds a separate 8-biomarker hormone kit for men, with an 8 to 11 biomarker range in its tier table.

What are the official 2026 membership prices for Empirical Health and Hone Health?

Empirical Health costs $190 once, and Hone Health bills monthly: $25 for Basic or $155 for Premium, plus medication.

The two pricing styles do not line up neatly. Hone's help center puts Basic at $300 a year and Premium at $1,860, and the first year adds a $25 test and a $25 onboarding fee on Basic, or a $65 test on Premium. That makes year one $350 and $1,925 before medication. Should the physician judge at that first consult that therapy is not appropriate, Hone hands back Premium's initial $155 fee, whereas Basic fees stay nonrefundable.

For comparison, Empirical's $399 Advanced program is the closest like-for-like, and it sits between Hone's two tiers. Hone's Plus program opens with a $45 at-home test and then costs $135 a month. Membership is month-to-month, and Hone says you can cancel anytime.

Empirical charges a $99 lab fee in New York and New Jersey. Both companies are HSA/FSA eligible, and Hone says eligibility depends on your plan.

How do doctor access and prescriptions compare?

Both give you prescriptions through a physician. What changes is where in the pricing the physician sits.

At Empirical, the doctor video visit belongs to the $399 program, and members can message doctors in the app.

At Hone, prescriptions are the center of the offer. Hone lists care categories including low testosterone, perimenopause and menopause, thyroid imbalance, sexual health, and heart health, with medication billed on top of the membership. Basic does not include hormone therapy.

How do collection and results timing differ?

Empirical's results mostly land in 3 to 5 business days, and the full set can take two to three weeks.

Hone's lab-processed results take about 10 business days at a lab, then a physician review of 1 to 2 business days before your consult is scheduled. At-home kits, which are for men, usually take about 4 business days once the lab has your sample.

Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

Book your test

Get 100+ biomarkers tested, in-lab or at home

One membership, one blood draw. Get a full picture of your health and the action plan you need to improve it.

Book your test

How do supplements and biological age compare?

Hone runs a first-party supplement storefront with nine own-brand products from $25 to $80, and Basic members get members-only pricing. Empirical has no supplement store.

Neither company publishes a biological age score. Empirical stays with cardiovascular health, and Hone's materials do not include one.

Where are Empirical Health and Hone Health tests available?

Both lean on 2,000+ partner labs, with Empirical using a national lab network, or a regional partner lab in New York and New Jersey, and Hone using that same national network. Arizona patients book with its regional affiliate.

Hone's state list offers no plan in Alaska, Arkansas, Connecticut, Delaware, the District of Columbia, Kansas, Louisiana, Minnesota, New Hampshire, New Jersey, North Dakota, Pennsylvania, Rhode Island, or South Carolina, and New York members cannot use Plus. Empirical's medical services reach people in over 30 states.

Who is Empirical Health best for, and who is Hone Health best for?

Empirical Health is best for:

People who want a one-time heart panel without a monthly bill.
People who want ApoB, Lp(a), and lifetime risk estimates in an app.
People who want a doctor visit and repeat testing at a flat $399.

Hone Health is best for:

People who want physician-led care, with medication delivered.
People who want a physician consult and a retest every 3 months.
People who want a low entry point, since Basic starts at $25 a month.

The bottom line

Empirical Health is a heart panel you buy once, with a doctor available one tier up. Hone Health is a clinic you subscribe to, where testing feeds ongoing care. Cardiovascular risk points to Empirical, and ongoing hormone care points to Hone.

Both put the physician behind a higher price. Empirical's visit comes with the $399 program, while Hone's is built into the $155-a-month Premium plan or sold on Basic at $75 to $100.

Superpower's membership is a flat $199 a year in most states, below Hone Basic's $300, and Empirical's panel runs $190 once. Hone Premium runs $1,860 a year before medication and adds physician consults every 3 months. Superpower AI builds your Superpower Protocol from labs, wearables, and records, with AI and care team support for questions along the way. Members get up to 20% off supplements through the marketplace, which also lists add-on tests and scans. Prescriptions are available there when clinically appropriate, priced separately. Superpower says 93% of members found their action plan more useful, even life-changing, than a yearly checkup.

Blood work is where a health plan starts, not where it ends. Build your home for health with Superpower today.